Meta-Analysis of the Prognostic Value of Narcotrend Monitoring of Different Depths of Anesthesia and Different Bispectral Index (BIS) Values for Cognitive Dysfunction after Tumor Surgery in Elderly Patients

Objective. To study the effect of Narcotrend monitoring on incidence early postoperative cognitive dysfunction (POCD) under different bispectral index (BIS) conditions and depths anesthesia POCD. Methods. We performed a literature search PubMed, Embase, OVID (database system made by Ovid Technologies, USA), CBM (Chinese Biomedical Literature database), CNKI (China National Knowledge Infrastructure), Wanfang, VIP databases (full-text database Chinese sci-tech journals), etc., from date establishment until December 31, 2020. Our meta-analysis was focused collection anesthesia. carefully read abstracts full texts randomized controlled trials POCD in period, their references were tracked. Data extraction quality evaluation included also performed, RevMan 5.3 software used for analysis. Results. In end, eight articles included, with total 714 patients. The results showed that four (255 patients) compared state deep (BIS 30–40) conventional 40–60 earlier) after Also, first day (Narcotrend stage (NTS): negative correlation is currently most appropriate EEG description; Nd can subdivide original into six stages 15 levels (Nd Sg, NTS), namely, A (state wakefulness) state, B0 B2 (sedated state), C0 C2 (light anesthetic D0 D2 (general anesthesia), E0–E1) significantly lower than (NTS DO–D1) (odds ratio (OR) = 0.21, 95% confidence interval (CI): 0.13–0.35, P < 0.00001 ). Moreover, E1) at 7 days surgery D0) (OR ratio) 0.45, CI: 0.23–0.91, id="M2"> = 0.03 ), while NTS 0.42, 0.24–0.71, id="M3"> 0.001 Discussion. Deep reduce 0.40, 0.22–0.73, id="M4"> 0.002 This three studies (216 BIS 40–50 50–60; did not 1.11, 0.24–5.24, id="M5"> 0.9